The VM group had significantly higher (P < .001) mean levels for serum testosterone ( nmol/L; range, -) and estradiol ( pmol/L; range, 79-941) in varicose saphenous veins compared with cubital veins (testosterone, nmol/L; range, -; estradiol, pmol/L; range, 31-147). Moreover, significantly (P < .001) higher mean serum estradiol levels ( pmol/L; range, 63-239) were detected in the saphenous veins of the HM group compared with cubital veins ( pmol/L; range, 37-153). Both groups had similar blood counts and serum androstenedione levels in the upper and lower extremity. Interestingly, qRT-PCR revealed that the mRNA expression of 5alpha-reductase type 1, 5alpha-reductase type 2, 17, 20 lyase, 17beta-hydroxysteroid dehydrogenase (17beta-HSD), aromatase and 3beta-HSD type 2, androgen and estrogen receptor 1 was down-regulated (P < .05) in all samples of varicose veins vs veins obtained from healthy men.
I get 2, 4 and 5 and I’m completely natural. I have had people accuse me of taking steroids many times and it pissed me off. It gets me to the point where I want to take steroids just so that I can say “Now this is me on steroids fckers!”. Lol. But nah I get a lot of acne outbreaks naturally and I have had many stretch marks as well as abnormally fast muscle gains. I’m a very lean person and when I stop working out I’m capable of drastically going from jacked to skinny as heck. When I start back up again I blow up quick. Another thing I’ve noticed is my pumps are naturally a lot more intense then the average lifter. Like my shoulders blow up like bowling balls and veins and shreds show up all over them along with my arm’s and chest. I’ve had a tone of people accuse me of taking steroids because of these factors. I also had a relative hug me once and say I was jacked and as solid as steal. He said only steroids do that. (He took steroids in the past) But it is to my understanding that muscle is solid… or at least a lot more solid than fat. At the time I was taking creatine and l-arginine with citrilline malate (which is a precursor to arginine) and a lot of BCAA’s.