In addition to the mentioned side effects several others have been reported. In both males and females acne are frequently reported, as well as hypertrophy of sebaceous glands, increased tallow excretion, hair loss, and alopecia. There is some evidence that anabolic steroid abuse may affect the immune system, leading to a decreased effectiveness of the defense system. Steroid use decreases the glucose tolerance, while there is an increase in insulin resistance. These changes mimic Type II diabetes. These changes seem to be reversible after abstention from the drugs.
Blood sugar levels issues are an exceptionally usual issue with the usage of prednisone. It is regular that sufferer in the medical hospital that are shifted even for short term corticosteroid treatment include their blood sugar levels seen thoroughly 2 to 3 times daily and handled with insulin whenever needed. Long-term utilize led to diabetes in up to 25% of people with up to 50% needing insulin after corticosteroid treatment was quit . Basically, about 12% of sufferer turn into long lasting diabetes patients with long lasting use of corticosteroids.
In general it has been found that oral steroids are more likely to prove detrimental to cardiovascular health than injectable forms of non C-17 alkyl steroids. In this regard it is important to point out that estrogen is actually known to have a positive effect on cholesterol levels, enhancing HDL levels, and keeping LDL levels under control. It is when aromatase inhibitors in ancillary compounds come into play during the steroid cycles that the individual is at risk of cardio-vascular diseases owing to estrogen levels being subdued. Further, it has been seen that when the individual is committed to a healthy diet that supports desired cholesterol levels during the steroid cycle , the risk of cardiovascular disease arising from steroid use can be kept under control.