The second case involved a 20-year-old male with ileocolic Crohn's disease and alopecia universalis. Five recurrent courses of antibiotics did not resolve his CDI but he became CDI-free after the FMT procedure. After transplantation, his hair loss improved from stage S4b alopecia (95–99% hair loss) to stage S2 (25–49% hair loss). Previous treatment with intralesional corticosteroid injections were ineffective and he only received two additional injections after FMT, which were administered to his scalp. However, after FMT he saw hair regrowth in not only his scalp, but other parts of the body as well. Related Articles
Steroid injections can prevent the immune system from attacking hair follicles in alopecia sufferers . This, in turn, can lead to hair regrowth. The treatment involves a steroid solution being injected directly into the scalp a number of times, and this may need to be repeated every few months. Whilst this treatment option is best suited to those with smaller patches of hair loss, it is still worth considering the long-term side effects of steroid injections which, ironically, can include premature balding. Steroid injections can also be extremely uncomfortable and painful.
In cases of severe hair loss, limited success has been achieved by using the corticosteroids clobetasol or fluocinonide , corticosteroid injections, or cream. The cream is not as effective and it takes longer in order to see results. Steroid injections are commonly used in sites where the areas of hair loss on the head are small or especially where eyebrow hair has been lost. Whether they are effective is uncertain. Some other medications that have been used are minoxidil , Elocon (mometasone) ointment (steroid cream), irritants (anthralin or topical coal tar), and topical immunotherapy ciclosporin , sometimes in different combinations. Topical corticosteroids frequently fail to enter the skin deeply enough to affect the hair bulbs, which are the treatment target,  and small lesions typically also regrow spontaneously. Oral corticosteroids decrease the hair loss, but only for the period during which they are taken, and these drugs can cause serious side effects .